Antifungals Overview
Invasive Fungal Infection1 (IFI):
Fungal bloodstream infections, primarily those caused by Candida species, are now the fourth most common bloodstream infection in the United States1.
Fungal bloodstream infections are associated with significant patient mortality and health care costs. Delaying the empiric treatment of Candida bloodstream infection until positive blood culture results are obtained is a potential risk factor for hospital mortality1.
Who Is at Risk?
Risk Factors For The Development of Candida Bloodstream Infection1:
- Previous administration of antibiotics
- Previous administration of corticosteroids
- Previous administration of chemotherapeutic agents
- Hematologic or solid-organ malignancy
- Neutropenia
- Extensive intra-abdominal surgery
- Burns
- Mechanical ventilation
- ICU admission
- Central Venous Catheter
- Parenteral nutrition
- Hemodialysis
- Prior fungal coolonization
Source: 1- Morrell M, Fraser V, Kollef M. Delaying the Empiric Treatment of Candida Bloodstream Infection until Positive Blood Culture Results are Obtained. Antimicrob Agents Chemother. 2005;49(9):3640–3645.
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AE-POS-00005| Expiry: 30-Apr-2022