Bangladesh H2H

*The monovalent human attenuated rotavirus vaccine
IgA,Immunoglobulin A

^aExclusion criteria include: received any rotavirus vaccine before enrolment; had any known allergies or sensitivity to rotavirus vaccines or their contents; had a history of intussusception, abdominal surgery, intestinal malformation, or a chronic medical condition identified by a medical officer; had a severe illness that required hospital admission; experienced vomiting or intolerance to liquids 24 hours before enrolment; received a rotavirus vaccine outside the study; identified a medical condition in which participation posed a risk (eg; bleeding disorder that would contraindicate collection of blood); received immunosuppressive medications; could not obtain blood during the first visit.¹

References :

1. Sharma S, Hagbom M, Svensson L, Nordgren J. The Impact of Human Genetic Polymorphisms on Rotavirus Susceptibility, Epidemiology, and Vaccine Take. Viruses. 2020;12(3):324. Published 2020 Mar 17. doi:10.3390/v12030324
2. Velasquez-Portocarrero DE, Wang X, Cortese MM, et al. Head-to-head comparison of the immunogenicity of RotaTeq and Rotarix rotavirus vaccines and factors associated with seroresponse in infants in Bangladesh: a randomised, controlled, open-label, parallel, phase 4 trial. Lancet Infect Dis. 2022;22(11):1606-1616. doi:10.1016/S1473-3099(22)00368